Mupirocin Topical Antibiotics

Mupirocin Topical Antibiotics

Each gram of Mupirocin Ointment (USP, 2% has 20 mg mupirocin per ml in a plain water miscible ointment) contains 20 mg of mupirocin. Mupirocin belongs to the group of antibiotics called broad spectrum inhibitors and is therefore effective against most gram-positive bacteria. This includes Streptococcus pneumoniae, Staphylococcus aureus and Candida albicans. It is used in the treatment of infections due to these bacteria and also as an antifungal agent. Studies have shown that mupirocin possesses some cytotoxic and antimicrobial properties.

Historical Background

Mupirocin was first tested in animals and showed good results at controlling the growth of several species of pathogenic bacteria such as E. coli and Enterobacteriaceae. Recently, several studies have been conducted to evaluate the ability of mupirocin ointment for various types of skin infections. These studies showed that the use of the medication is effective in both reducing the intensity and duration of skin infections caused by these bacteria. The medication is also able to prevent the bacterial colonization of the skin.


A clinical trial was conducted to evaluate the effectiveness of mupirocin ointment for the treatment of ringworm. A total area of approximately 70 square centimeters was treated with the medication for ten days. One gram of mupirocin ointment was administered on the infected area may minimize the appearance of the disease for at least three days. The fungus usually shows up as red circular scaly spots. The lesions usually appear on the legs, armpits, and feet.

One significant benefit associated with the use of mupirocin ointment is for the prevention of bacterial contamination. This can be achieved by reducing the number of potential sources of infection. These include skin and other sites in which contact with bacteria can occur, such as the rectum, vagina, mouth, and toes. The medication can also help prevent the occurrence of renal impairment, which is a complication that can occur when a person is infected with bacteria carrying the pathogen. This complication can result to a form of shock or kidney failure.

Infection Prevention

Aside from the prevention of infections, mupirocin ointment can also minimize irritation and discomfort caused by rashes and lesions. The inflammation usually occurs during the acute infection. However, irritation can be prevented if the medication is applied on the site. This will allow doctors to assess the extent of the infection and decide whether treatment is required or not.

Studies have shown that the risks of infections and other complications can be minimized if the dosage of mupirocin ointment is administered on time. However, an overdose may lead to more complications. Overdosing with mupirocin can lead to liver damage, kidney damage, and sometimes coma and death. This is why overdose is strictly prohibited and reported to the proper authorities.

Bacterial Infection

It is very important that people suffering from skin infections should not administer mupirocin ointment on their own. Instead, they should seek medical attention. The administration of mupirocin on your own might worsen the condition and cause bacterial infections. This is especially true for children who have an immature immune system.

Consult Doctor

If you think that mupirocin ointment might be useful for your condition, you should consult with your doctor. Your physician will be able to help you decide whether this medication is the right one for you. You should also keep in mind that even though the brand name of this medication is indicated on the bottle, it does not mean that this drug has the same effect on all types of infections. You should remember that no two people, male and female, respond the same way to medications and treatments.

Common Side Effects

Common side effects of mupirocin are nausea, diarrhea, stomach cramps, and itching or burning sensations. Some patients experience vomiting, dizziness, and severe skin allergies. For most patients, these symptoms subside within 24 hours of beginning treatment. Rare but possible side effects include seizures, difficulty breathing, problems with vision, and liver damage.

There is a possible concern with using mupirocin ointment for skin infections, especially if you have a history of allergic reactions to this medication. To be safe, try to see a doctor before trying this treatment. If you suffer from any type of kidney disease or liver problems, you should consult with your doctor before starting mupirocin. You should also avoid taking this medication if you have a history of infections in the nose, throat, or mouth. You should also avoid using this ointment if you have any type of heart or lung disease or if you have diabetes.

It is recommended that anytime you treat skin infections with mupirocin, you do so under medical supervision. Use a moisturizer with sunscreen, such as the Lifecell Dermal Moisture Spot, which can help to protect against UV light from the sun. Don’t get the treatment on hands or fingers. Before applying mupirocin topical products, clean the area with rubbing alcohol or disinfectant. Then, apply the treatment. Patience is the key to treating impetigo.

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